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BAS YEH SAMJ LO. 🏆🏆🏆🩵✅ Ek type 2 diabetes ke sharir mein actually aur issi gap ko samjte hue hamne banaya rediclinic diacontrol * Insulin resistance (hallmark) * Relative insulin deficiency * Hyperinsulinemia (early stage) * β-cell dysfunction/failure (late stage) * Obesity (especially central obesity) * Metabolic syndrome * Acanthosis nigricans * Sedentary lifestyle * Family history * Adult-onset diabetes (though now seen in younger people too) * Polyuria, polydipsia, polyphagia * Non-ketotic hyperglycemia * Hyperosmolar Hyperglycemic State (HHS) – classic acute complication * Microvascular complications – retinopathy, nephropathy, neuropathy * Macrovascular complications – coronary artery disease, stroke, peripheral arterial disease * HbA1c ≥ 6.5% * Fasting plasma glucose ≥ 126 mg/dL * Random plasma glucose ≥ 200 mg/dL (with symptoms) * Lifestyle modification – first step in management * Metformin – first-line drug * SGLT2 inhibitors – heart failure and CKD benefit * GLP-1 receptor agonists – weight loss and cardiovascular benefit * Hypoglycemia – common with insulin and sulfonylureas * Diabetic foot * Non-alcoholic fatty liver disease (NAFLD) association jo sabse pehle aapke pancreas mein b cells ko support karta hai insuln prodcution mein so insulinn increase then uske sensitivoty increase karta hai jisse aapke cells aur liver uske signals ko samjhne lagte hai jisse 0 dependency aur better sugar remission ke chances toh abhi iss loop se bahar aayie aur neeche diye gaye order pe tap kariye #doctor #pharma #pharmacists #health #rediclinic